Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States.
نویسندگان
چکیده
Two genomes of a new porcine circovirus type 2 (PCV2) strain associated with cases of perceived failure of PCV2 vaccination were sequenced and analyzed. Based on the genome, this is the first report of this mutant of PCV2b in the United States. The genomic knowledge of this mutant PCV2b will improve understanding of the epidemiology of PCV and potentially inform the development of new and more effective vaccines for PCV2.
منابع مشابه
Phylodynamic analysis of porcine circovirus type 2: Methodological approach and datasets
Since its first description, PCV2 has emerged as one of the most economically relevant diseases for the swine industry. Despite the introduction of vaccines effective in controlling clinical syndromes, PCV2 spread was not prevented and some potential evidences of vaccine immuno escape have recently been reported ("Complete genome sequence of a novel porcine circovirus type 2b variant present in...
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ورودعنوان ژورنال:
- Journal of virology
دوره 86 22 شماره
صفحات -
تاریخ انتشار 2012